22GS
HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y49F MUTANT
Summary for 22GS
Entry DOI | 10.2210/pdb22gs/pdb |
Descriptor | GLUTATHIONE S-TRANSFERASE P1-1, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total) |
Functional Keywords | transferase, glutathione, pi, detoxification, y49f |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P09211 |
Total number of polymer chains | 2 |
Total formula weight | 47309.25 |
Authors | Oakley, A.J. (deposition date: 1998-03-10, release date: 1999-03-23, Last modification date: 2024-05-22) |
Primary citation | Ortiz-Salmeron, E.,Nuccetelli, M.,Oakley, A.J.,Parker, M.W.,Lo Bello, M.,Garcia-Fuentes, L. Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione. J.Biol.Chem., 278:46938-46948, 2003 Cited by PubMed: 12937169DOI: 10.1074/jbc.M305043200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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