216D

CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN

216D の概要

• エントリーDOI: 10.2210/pdb216d/pdb
• 分子名称: DNA/RNA (5'-D(*IP*)-R(*CP*)-D(*IP*CP*IP*CP*IP*C)-3'), DISTAMYCIN A, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: b-dna/rna, double helix, complexed with drug, modified, dna-rna hybrid
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2890.35

構造登録者

Chen, X.,Ramakrishnan, B.,Sundaralingam, M. (登録日: 1995-07-18, 公開日: 1996-01-29, 最終更新日: 2024-02-14)

主引用文献

Chen, X.,Ramakrishnan, B.,Sundaralingam, M.
Crystal structures of B-form DNA-RNA chimers complexed with distamycin.
Nat.Struct.Biol., 2:733-735, 1995

PubMed Abstract: Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.

PubMed: 7552741
DOI: 10.1038/nsb0995-733

実験手法

X-RAY DIFFRACTION (1.73 Å)