1ZYM

AMINO TERMINAL DOMAIN OF ENZYME I FROM ESCHERICHIA COLI

1ZYM の概要

• エントリーDOI: 10.2210/pdb1zym/pdb
• 分子名称: ENZYME I (2 entities in total)
• 機能のキーワード: phosphotransferase
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P08839
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 56448.24

構造登録者

Liao, D.-I.,Davies, D.R. (登録日: 1996-05-21, 公開日: 1996-12-07, 最終更新日: 2024-02-14)

主引用文献

Liao, D.I.,Silverton, E.,Seok, Y.J.,Lee, B.R.,Peterkofsky, A.,Davies, D.R.
The first step in sugar transport: crystal structure of the amino terminal domain of enzyme I of the E. coli PEP: sugar phosphotransferase system and a model of the phosphotransfer complex with HPr.
Structure, 4:861-872, 1996

PubMed Abstract: The bacterial phosphoenolpyruvate (PEP): sugar phosphotransferase system (PTS) transports exogenous hexose sugars through the membrane and tightly couples transport with phosphoryl transfer from PEP to the sugar via several phosphoprotein intermediates. The phosphate group is first transferred to enzyme I, second to the histidine-containing phosphocarrier protein HPr, and then to one of a number of sugar-specific enzymes II. The structures of several HPrs and enzymes IIA are known. Here we report the structure of the N-terminal half of enzyme I from Escherichia coli (EIN).

PubMed: 8805571
DOI: 10.1016/S0969-2126(96)00092-5

実験手法

X-RAY DIFFRACTION (2.5 Å)