1ZTK

Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide

1ZTK の概要

• エントリーDOI: 10.2210/pdb1ztk/pdb
• 分子名称: Coagulation factor XI, SULFATE ION, 2-(5-AMINO-6-OXO-2-M-TOLYL-6H-PYRIMIDIN-1-YL)-N-[4-GUANIDINO-1-(THIAZOLE-2-CARBONYL)-BUTYL]-ACETAMIDE, ... (4 entities in total)
• 機能のキーワード: fxia, inhibitors, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P03951
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27427.05

構造登録者

Nagafuji, P.,Jin, L.,Rynkiewicz, M.,Quinn, J.,Bibbins, F.,Meyers, H.,Babine, R.E.,Strickler, J.E.,Abdel-Meguid, S.S. (登録日: 2005-05-27, 公開日: 2006-05-09, 最終更新日: 2024-12-25)

• 主引用文献: Nagafuji, P.,Jin, L.,Rynkiewicz, M.,Quinn, J.,Bibbins, F.,Meyers, H.,Babine, R.E.,Strickler, J.E.,Abdel-Meguid, S.S.; Pyrimidinone Inhibitors of a Thrombolytic Protease; To be Published,

実験手法

X-RAY DIFFRACTION (2.5 Å)