1ZCM
Human calpain protease core inhibited by ZLLYCH2F
Summary for 1ZCM
| Entry DOI | 10.2210/pdb1zcm/pdb |
| Descriptor | Calpain 1, large [catalytic] subunit, CALCIUM ION, N-[(BENZYLOXY)CARBONYL]LEUCYL-N~1~-[3-FLUORO-1-(4-HYDROXYBENZYL)-2-OXOPROPYL]LEUCINAMIDE, ... (4 entities in total) |
| Functional Keywords | calcium binding, hydrolase, protease, thiol protease |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : P07384 |
| Total number of polymer chains | 1 |
| Total formula weight | 37001.79 |
| Authors | Li, Q.,Hanzlik, R.P.,Weaver, R.F.,Schonbrunn, E. (deposition date: 2005-04-12, release date: 2006-01-31, Last modification date: 2023-08-23) |
| Primary citation | Li, Q.,Hanzlik, R.P.,Weaver, R.F.,Schonbrunn, E. Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core Biochemistry, 45:701-708, 2006 Cited by PubMed: 16411745DOI: 10.1021/bi052077b PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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