1ZA3

The crystal structure of the YSd1 Fab bound to DR5

Summary for 1ZA3

• Entry DOI: 10.2210/pdb1za3/pdb
• Related: 1d0g
• Descriptor: Fab-YSd1 light chain, Fab-YSd1 heavy chain, Tumor necrosis factor receptor superfamily member 10B (3 entities in total)
• Functional Keywords: phage display, protein engineering, combinatorial mutagenesis, antibody library, death receptor-5, immune system-signaling protein complex, immune system/signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: O14763
• Total number of polymer chains: 6
• Total formula weight: 126742.72

Authors

Fellouse, F.A.,Li, B.,Compaan, D.M.,Peden, A.A.,Hymowitz, S.G.,Sidhu, S.S. (deposition date: 2005-04-05, release date: 2005-06-14, Last modification date: 2023-08-23)

• Primary citation: Fellouse, F.A.,Li, B.,Compaan, D.M.,Peden, A.A.,Hymowitz, S.G.,Sidhu, S.S.; Molecular recognition by a binary code.; J.Mol.Biol., 348:1153-1162, 2005; PubMed: 15854651; DOI: 10.1016/j.jmb.2005.03.041

Experimental method

X-RAY DIFFRACTION (3.35 Å)