1Z9A

Crystal Structure Of The Asn-309 To Asp Mutant Of Candida Tenuis Xylose Reductase (Akr2B5) Bound To Nad+

Summary for 1Z9A

Entry DOI	10.2210/pdb1z9a/pdb
Descriptor	NAD(P)H-dependent D-xylose reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	beta-alpha-barrel, akr, aldo-keto reductase, xylose reductase, candida tenuis, substrate selectivity, ketone reduction, structure-activity correlation, oxidoreductase
Biological source	Candida tenuis
Total number of polymer chains	4
Total formula weight	146381.67
Authors	Kratzer, R.,Leitgeb, S.,Wilson, D.K.,Nidetzky, B. (deposition date: 2005-04-01, release date: 2006-01-03, Last modification date: 2024-04-03)
Primary citation	Kratzer, R.,Leitgeb, S.,Wilson, D.K.,Nidetzky, B. Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis Biochem.J., 393:51-58, 2006 Cited by PubMed: 16336198 DOI: 10.1042/BJ20050831 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation