1Z9A
Crystal Structure Of The Asn-309 To Asp Mutant Of Candida Tenuis Xylose Reductase (Akr2B5) Bound To Nad+
Summary for 1Z9A
Entry DOI | 10.2210/pdb1z9a/pdb |
Descriptor | NAD(P)H-dependent D-xylose reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total) |
Functional Keywords | beta-alpha-barrel, akr, aldo-keto reductase, xylose reductase, candida tenuis, substrate selectivity, ketone reduction, structure-activity correlation, oxidoreductase |
Biological source | Candida tenuis |
Total number of polymer chains | 4 |
Total formula weight | 146381.67 |
Authors | Kratzer, R.,Leitgeb, S.,Wilson, D.K.,Nidetzky, B. (deposition date: 2005-04-01, release date: 2006-01-03, Last modification date: 2024-04-03) |
Primary citation | Kratzer, R.,Leitgeb, S.,Wilson, D.K.,Nidetzky, B. Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis Biochem.J., 393:51-58, 2006 Cited by PubMed: 16336198DOI: 10.1042/BJ20050831 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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