1Z9A

Crystal Structure Of The Asn-309 To Asp Mutant Of Candida Tenuis Xylose Reductase (Akr2B5) Bound To Nad+

1Z9A の概要

• エントリーDOI: 10.2210/pdb1z9a/pdb
• 分子名称: NAD(P)H-dependent D-xylose reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: beta-alpha-barrel, akr, aldo-keto reductase, xylose reductase, candida tenuis, substrate selectivity, ketone reduction, structure-activity correlation, oxidoreductase
• 由来する生物種: Candida tenuis
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 146381.67

構造登録者

Kratzer, R.,Leitgeb, S.,Wilson, D.K.,Nidetzky, B. (登録日: 2005-04-01, 公開日: 2006-01-03, 最終更新日: 2024-04-03)

• 主引用文献: Kratzer, R.,Leitgeb, S.,Wilson, D.K.,Nidetzky, B.; Probing the substrate binding site of Candida tenuis xylose reductase (AKR2B5) with site-directed mutagenesis; Biochem.J., 393:51-58, 2006; PubMed: 16336198; DOI: 10.1042/BJ20050831

実験手法

X-RAY DIFFRACTION (2.4 Å)