1Z8R

2A cysteine proteinase from human coxsackievirus B4 (strain JVB / Benschoten / New York / 51)

Summary for 1Z8R

• Entry DOI: 10.2210/pdb1z8r/pdb
• NMR Information: BMRB: 6613
• Descriptor: Coxsackievirus B4 polyprotein, ZINC ION (2 entities in total)
• Functional Keywords: beta barrel coordinated zinc ion, hydrolase
• Biological source: Human coxsackievirus B4
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P08292
• Total number of polymer chains: 1
• Total formula weight: 18491.93

Authors

Baxter, N.J.,Roetzer, A.,Liebig, H.D.,Sedelnikova, S.E.,Hounslow, A.M.,Skern, T.,Waltho, J.P. (deposition date: 2005-03-31, release date: 2006-02-14, Last modification date: 2021-10-20)

• Primary citation: Baxter, N.J.,Roetzer, A.,Liebig, H.D.,Sedelnikova, S.E.,Hounslow, A.M.,Skern, T.,Waltho, J.P.; Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease.; J.Virol., 80:1451-1462, 2006; PubMed: 16415022; DOI: 10.1128/JVI.80.3.1451-1462.2006

Experimental method

SOLUTION NMR