1Z8R

2A cysteine proteinase from human coxsackievirus B4 (strain JVB / Benschoten / New York / 51)

1Z8R の概要

• エントリーDOI: 10.2210/pdb1z8r/pdb
• NMR情報: BMRB: 6613
• 分子名称: Coxsackievirus B4 polyprotein, ZINC ION (2 entities in total)
• 機能のキーワード: beta barrel coordinated zinc ion, hydrolase
• 由来する生物種: Human coxsackievirus B4
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P08292
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18491.93

構造登録者

Baxter, N.J.,Roetzer, A.,Liebig, H.D.,Sedelnikova, S.E.,Hounslow, A.M.,Skern, T.,Waltho, J.P. (登録日: 2005-03-31, 公開日: 2006-02-14, 最終更新日: 2021-10-20)

• 主引用文献: Baxter, N.J.,Roetzer, A.,Liebig, H.D.,Sedelnikova, S.E.,Hounslow, A.M.,Skern, T.,Waltho, J.P.; Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease.; J.Virol., 80:1451-1462, 2006; PubMed: 16415022; DOI: 10.1128/JVI.80.3.1451-1462.2006

実験手法

SOLUTION NMR