1Z7J
Human transthyretin (also called prealbumin) complex with 3, 3',5,5'-tetraiodothyroacetic acid (t4ac)
Replaces: 1KEDSummary for 1Z7J
Entry DOI | 10.2210/pdb1z7j/pdb |
Related | 1PAB 2ROX |
Descriptor | Transthyretin, 3,3',5,5'-TETRAIODOTHYROACETIC ACID (3 entities in total) |
Functional Keywords | albumin, transport, retinol-binding, vitamin a, amyloid, thyroid hormone, liver, plasma, cerebrospinal fluid, polyneuropathy, disease mutation, tetraiodothyroacetic acid, t4ac, prealbumin, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 29050.38 |
Authors | Neumann, P.,Wojtczak, A.,Cody, V. (deposition date: 2005-03-25, release date: 2005-06-07, Last modification date: 2023-08-23) |
Primary citation | Neumann, P.,Cody, V.,Wojtczak, A. Ligand binding at the transthyretin dimer-dimer interface: structure of the transthyretin-T4Ac complex at 2.2 Angstrom resolution. Acta Crystallogr.,Sect.D, 61:1313-1319, 2005 Cited by PubMed: 16204882DOI: 10.1107/S0907444905022523 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report