1Z68

Crystal Structure Of Human Fibroblast Activation Protein alpha

1Z68 の概要

• エントリーDOI: 10.2210/pdb1z68/pdb
• 分子名称: fibroblast activation protein, alpha subunit, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: seprase, fibroblast activation protein alpha, fapalpha, dipeptidylpeptidase, s9b, integral membrane serine protease, lyase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Single-pass type II membrane protein: Q12884
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 169170.11

構造登録者

Aertgeerts, K.,Levin, I.,Shi, L.,Prasad, G.S.,Zhang, Y.,Kraus, M.L.,Salakian, S.,Snell, G.P.,Sridhar, V.,Wijnands, R.,Tennant, M.G. (登録日: 2005-03-21, 公開日: 2005-04-12, 最終更新日: 2023-08-23)

• 主引用文献: Aertgeerts, K.,Levin, I.,Shi, L.,Snell, G.P.,Jennings, A.,Prasad, G.S.,Zhang, Y.,Kraus, M.L.,Salakian, S.,Sridhar, V.,Wijnands, R.,Tennant, M.G.; Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha.; J.Biol.Chem., 280:19441-19444, 2005; PubMed: 15809306; DOI: 10.1074/jbc.C500092200

実験手法

X-RAY DIFFRACTION (2.6 Å)