Summary for 1Z1H
| Entry DOI | 10.2210/pdb1z1h/pdb |
| Related | 1B6J 1B6K 1B6L 1B6M 1B6N 1B6P |
| Descriptor | Pol polyprotein, SULFATE ION, N-{(2R)-2-HYDROXY-2-[(8S,11S)-8-ISOPROPYL-6,9-DIOXO-2-OXA-7,10-DIAZABICYCLO[11.2.2]HEPTADECA-1(15),13,16-TRIEN-11-YL]ETHYL}-N-ISOPENTYLBENZENESULFONAMIDE, ... (4 entities in total) |
| Functional Keywords | macrocyclic inhibitors, peptidomimetic inhibitors, hiv1 protease, hydrolase |
| Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03369 |
| Total number of polymer chains | 2 |
| Total formula weight | 22489.37 |
| Authors | Martin, J.L.,Begun, J.,Schindeler, A.,Wickramasinghe, W.A.,Alewood, D.,Alewood, P.F.,Bergman, D.A.,Brinkworth, R.I.,Abbenante, G.,March, D.R.,Reid, R.C.,Fairlie, D.P. (deposition date: 2005-03-04, release date: 2005-03-22, Last modification date: 2023-11-15) |
| Primary citation | Martin, J.L.,Begun, J.,Schindeler, A.,Wickramasinghe, W.A.,Alewood, D.,Alewood, P.F.,Bergman, D.A.,Brinkworth, R.I.,Abbenante, G.,March, D.R.,Reid, R.C.,Fairlie, D.P. Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease Biochemistry, 38:7978-7988, 1999 Cited by PubMed: 10387041DOI: 10.1021/bi990174x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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