1YYP

Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54

1YYP の概要

• エントリーDOI: 10.2210/pdb1yyp/pdb
• 関連するPDBエントリー: 1T6L
• 分子名称: DNA polymerase processivity factor, DNA polymerase, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: processivity fold (same fold as hsv ul42, pcna, and homotrimeric sliding clamps), replication-transferase complex, replication/transferase
• 由来する生物種: Human herpesvirus 5 (Human cytomegalovirus)
• 細胞内の位置: Virion: P16790; Host nucleus : P08546
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35732.04

構造登録者

Appleton, B.A.,Brooks, J.,Loregian, A.,Filman, D.J.,Coen, D.M.,Hogle, J.M. (登録日: 2005-02-25, 公開日: 2005-12-27, 最終更新日: 2024-02-14)

• 主引用文献: Appleton, B.A.,Brooks, J.,Loregian, A.,Filman, D.J.,Coen, D.M.,Hogle, J.M.; Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44.; J.Biol.Chem., 281:5224-5232, 2006; PubMed: 16371349; DOI: 10.1074/jbc.M506900200

実験手法

X-RAY DIFFRACTION (2.5 Å)