1YYM

crystal structure of F23, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 gp120 envelope glycoprotein and anti-HIV-1 antibody 17b

1YYM の概要

• エントリーDOI: 10.2210/pdb1yym/pdb
• 関連するPDBエントリー: 1YYL
• 分子名称: Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120),Exterior membrane glycoprotein(GP120), antibody 17b light chain, antibody 17b heavy chain, ... (8 entities in total)
• 機能のキーワード: hiv-1, gp120, yu2, scorpion toxin, cd4 mimic, f23, antibody, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 174902.69

構造登録者

Huang, C.C.,Stricher, F.,Martin, L.,Decker, J.M.,Majeed, S.,Barthe, P.,Hendrickson, W.A.,Robinson, J.,Roumestand, C.,Sodroski, J.,Wyatt, R.,Shaw, G.M.,Vita, C.,Kwong, P.D. (登録日: 2005-02-25, 公開日: 2005-05-03, 最終更新日: 2023-10-25)

• 主引用文献: Huang, C.C.,Stricher, F.,Martin, L.,Decker, J.M.,Majeed, S.,Barthe, P.,Hendrickson, W.A.,Robinson, J.,Roumestand, C.,Sodroski, J.,Wyatt, R.,Shaw, G.M.,Vita, C.,Kwong, P.D.; Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth.; Structure, 13:755-768, 2005; PubMed: 15893666; DOI: 10.1016/j.str.2005.03.006

実験手法

X-RAY DIFFRACTION (2.2 Å)