1YY0

Crystal structure of an RNA duplex containing a 2'-amine substitution and a 2'-amide product produced by in-crystal acylation at a C-A mismatch

1YY0 の概要

• エントリーDOI: 10.2210/pdb1yy0/pdb
• 分子名称: 5'-R(*GP*CP*AP*GP*AP*(A5M)P*UP*UP*AP*AP*AP*UP*CP*UP*GP*C)-3', 5'-R(*GP*CP*AP*GP*AP*(M5M)P*UP*UP*AP*AP*AP*UP*CP*UP*GP*C)-3', CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: 2'-amine, rna, duplex, mismatch, 2-amide, in-crystal reaction
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 15365.47

構造登録者

Gherghe, C.M.,Krahn, J.M.,Weeks, K.M. (登録日: 2005-02-23, 公開日: 2005-10-18, 最終更新日: 2024-02-14)

• 主引用文献: Gherghe, C.M.,Krahn, J.M.,Weeks, K.M.; Crystal structures, reactivity and inferred acylation transition States for 2'-amine substituted RNA.; J.Am.Chem.Soc., 127:13622-13628, 2005; PubMed: 16190727; DOI: 10.1021/ja053647y

実験手法

X-RAY DIFFRACTION (3.2 Å)