1YWO

Phospholipase Cgamma1 SH3 in complex with a SLP-76 motif

Summary for 1YWO

Entry DOI	10.2210/pdb1ywo/pdb
Descriptor	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1, Lymphocyte cytosolic protein 2 (3 entities in total)
Functional Keywords	sh3, phospholipase c-gamma1, slp-76, sh2 domain-containing leukocyte phosphoprotein of 76 kd, hydrolase, signaling protein
Biological source	Rattus norvegicus (Norway rat) More
Cellular location	Cytoplasm (Probable): P10686 Cell projection, lamellipodium (By similarity): Q13094
Total number of polymer chains	2
Total formula weight	8561.63
Authors	Deng, L.,Velikovsky, C.A.,Swaminathan, C.P.,Cho, S.,Mariuzza, R.A. (deposition date: 2005-02-18, release date: 2005-08-16, Last modification date: 2024-02-14)
Primary citation	Deng, L.,Velikovsky, C.A.,Swaminathan, C.P.,Cho, S.,Mariuzza, R.A. Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cgamma1 J.Mol.Biol., 352:1-10, 2005 Cited by PubMed: 16061254 DOI: 10.1016/j.jmb.2005.06.072 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.81 Å)

Structure validation