1YT9
HIV Protease with oximinoarylsulfonamide bound
Summary for 1YT9
Entry DOI | 10.2210/pdb1yt9/pdb |
Related | 1MUI |
Descriptor | Pol polyprotein, (S)-N-((2S,3R)-3-HYDROXY-4-(4-((E)-(HYDROXYIMINO)METHYL)-N-ISOBUTYLPHENYLSULFONAMIDO)-1-PHENYLBUTAN-2-YL)-3-METHYL-2-(3 -((2-METHYLTHIAZOL-4-YL)METHYL)-2-OXOIMIDAZOLIDIN-1-YL)BUTANAMIDE (2 entities in total) |
Functional Keywords | hiv protease, oximinoarylsulfonamides, hydrolase |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 22306.41 |
Authors | Yeung, C.M.,Klein, L.L.,Flentge, C.A.,Randolph, J.T.,Zhao, C.,Sun, M.,Dekhtyar, T.,Stoll, V.S.,Kempf, D.J. (deposition date: 2005-02-10, release date: 2005-04-12, Last modification date: 2024-02-14) |
Primary citation | Yeung, C.M.,Klein, L.L.,Flentge, C.A.,Randolph, J.T.,Zhao, C.,Sun, M.,Dekhtyar, T.,Stoll, V.S.,Kempf, D.J. Oximinoarylsulfonamides as potent HIV protease inhibitors. Bioorg.Med.Chem.Lett., 15:2275-2278, 2005 Cited by PubMed: 15837308DOI: 10.1016/j.bmcl.2005.03.008 PDB entries with the same primary citation |
Experimental method |
Structure validation
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