1YRY

Crystal structure of human PNP complexed with MESG

1YRY の概要

• エントリーDOI: 10.2210/pdb1yry/pdb
• 分子名称: Purine nucleoside phosphorylase, SULFATE ION, 7-METHYL-6-THIO-GUANOSINE, ... (4 entities in total)
• 機能のキーワード: purine nucleoside phosphorylase, drug design, synchrotron, mesg, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm, cytoskeleton (By similarity): P00491
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32786.40

構造登録者

Silva, R.G.,Pereira, J.H.,Canduri, F.,Basso, L.A.,de Azevedo Jr., W.F.,Santos, D.S. (登録日: 2005-02-05, 公開日: 2006-01-17, 最終更新日: 2023-10-25)

• 主引用文献: Silva, R.G.,Pereira, J.H.,Canduri, F.,de Azevedo Jr., W.F.,Basso, L.A.,Santos, D.S.; Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine; Arch.Biochem.Biophys., 442:49-58, 2005; PubMed: 16154528; DOI: 10.1016/j.abb.2005.07.021

実験手法

X-RAY DIFFRACTION (2.8 Å)