1YMX
X-ray crystallographic structure of CTX-M-9 beta-lactamase covalently linked to cefoxitin
Summary for 1YMX
Entry DOI | 10.2210/pdb1ymx/pdb |
Related | 1YLJ 1YLY 1YM1 1YMS |
Descriptor | beta-lactamase CTX-M-9, (2R)-5-[(carbamoyloxy)methyl]-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid (3 entities in total) |
Functional Keywords | ctx-m, beta-lactamase, acyl-enzyme complex, cefoxitin, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 56803.92 |
Authors | Chen, Y.,Shoichet, B.,Bonnet, R. (deposition date: 2005-01-21, release date: 2005-04-26, Last modification date: 2023-08-23) |
Primary citation | Chen, Y.,Shoichet, B.,Bonnet, R. Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127:5423-5434, 2005 Cited by PubMed: 15826180DOI: 10.1021/ja042850a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report