1YLY

X-ray crystallographic structure of CTX-M-9 beta-lactamase complexed with ceftazidime-like boronic acid

Summary for 1YLY

Entry DOI	10.2210/pdb1yly/pdb
Related	1YLJ
Descriptor	beta-lactamase CTX-M-9, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	ctx-m, beta-lactamase, transition state, ceftazidime, boronic acid, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	56795.18
Authors	Chen, Y.,Shoichet, B.,Bonnet, R. (deposition date: 2005-01-19, release date: 2005-04-26, Last modification date: 2023-08-23)
Primary citation	Chen, Y.,Shoichet, B.,Bonnet, R. Structure, Function, and Inhibition along the Reaction Coordinate of CTX-M beta-Lactamases. J.Am.Chem.Soc., 127:5423-5434, 2005 Cited by PubMed: 15826180 DOI: 10.1021/ja042850a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation