1YHW

Crystal Structure of PAK1 kinase domain with one point mutations (K299R)

Summary for 1YHW

Related1YHV
DescriptorSerine/threonine-protein kinase PAK 1 (2 entities in total)
Functional Keywordskinase; active conformation; activation loop; atp binding site, signaling protein, transferase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q13153
Total number of polymer chains1
Total molecular weight33273.23
Authors
Lei, M.,Robinson, M.A.,Harrison, S.C. (deposition date: 2005-01-10, release date: 2005-05-24, Last modification date: 2011-07-13)
Primary citation
Lei, M.,Robinson, M.A.,Harrison, S.C.
The Active Conformation of the PAK1 Kinase Domain
Structure, 13:769-778, 2005
PubMed: 15893667 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2005.03.007
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.243351.7%3.2%8.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution