1YCE

Structure of the rotor ring of F-type Na+-ATPase from Ilyobacter tartaricus

1YCE の概要

• エントリーDOI: 10.2210/pdb1yce/pdb
• 分子名称: subunit c, SODIUM ION, NONAN-1-OL, ... (4 entities in total)
• 機能のキーワード: atp synthase, na binding site, membrane protein
• 由来する生物種: Ilyobacter tartaricus
• タンパク質・核酸の鎖数: 44
• 化学式量合計: 394528.11

構造登録者

Meier, T.,Polzer, P.,Diederichs, K.,Welte, W.,Dimroth, P. (登録日: 2004-12-22, 公開日: 2005-04-12, 最終更新日: 2024-02-14)

主引用文献

Meier, T.,Polzer, P.,Diederichs, K.,Welte, W.,Dimroth, P.
Structure of the rotor ring of F-Type Na+-ATPase from Ilyobacter tartaricus.
Science, 308:659-662, 2005

PubMed Abstract: In the crystal structure of the membrane-embedded rotor ring of the sodium ion-translocating adenosine 5'-triphosphate (ATP) synthase of Ilyobacter tartaricus at 2.4 angstrom resolution, 11 c subunits are assembled into an hourglass-shaped cylinder with 11-fold symmetry. Sodium ions are bound in a locked conformation close to the outer surface of the cylinder near the middle of the membrane. The structure supports an ion-translocation mechanism in the intact ATP synthase in which the binding site converts from the locked conformation into one that opens toward subunit a as the rotor ring moves through the subunit a/c interface.

PubMed: 15860619
DOI: 10.1126/science.1111199

実験手法

X-RAY DIFFRACTION (2.4 Å)