1YAH

Crystal Structure of Human Liver Carboxylesterase complexed to Etyl Acetate; A Fatty Acid Ethyl Ester Analogue

1YAH の概要

• エントリーDOI: 10.2210/pdb1yah/pdb
• 関連するPDBエントリー: 1MX1 1MX5 1MX9 1ya4 1ya8 1yaj
• 分子名称: CES1 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, ... (6 entities in total)
• 機能のキーワード: hydrolase, carboxylesterase, ethyl acetate, fatty acid acyl ester
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 178713.12

構造登録者

Fleming, C.D.,Bencahrit, S.,Edwards, C.C.,Hyatt, J.L.,Morton, C.L.,Howard-Williams, E.L.,Potter, P.M.,Redinbo, M.R. (登録日: 2004-12-17, 公開日: 2005-08-02, 最終更新日: 2023-08-23)

• 主引用文献: Fleming, C.D.,Bencharit, S.,Edwards, C.C.,Hyatt, J.L.,Tsurkan, L.,Bai, F.,Fraga, C.,Morton, C.L.,Howard-Williams, E.L.,Potter, P.M.,Redinbo, M.R.; Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.; J.Mol.Biol., 352:165-177, 2005; PubMed: 16081098; DOI: 10.1016/j.jmb.2005.07.016

実験手法

X-RAY DIFFRACTION (3 Å)