1Y6O

Crystal structure of disulfide engineered porcine pancreatic phospholipase A2 to group-X isozyme in complex with inhibitor MJ33 and phosphate ions

Summary for 1Y6O

• Entry DOI: 10.2210/pdb1y6o/pdb
• Related: 1FXF 1LE6 1Y6P
• Descriptor: Phospholipase A2, major isoenzyme, CALCIUM ION, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: hydrolase. disulfide engineered pla2. porcine pancratic isozyme., hydrolase
• Biological source: Sus scrofa (pig)
• Cellular location: Secreted: P00592
• Total number of polymer chains: 2
• Total formula weight: 31250.05

Authors

Yu, B.Z.,Pan, Y.H.,Jassen, M.J.W.,Bahnson, B.J.,Jain, M.K. (deposition date: 2004-12-06, release date: 2005-03-22, Last modification date: 2023-08-23)

• Primary citation: Yu, B.Z.,Pan, Y.H.,Janssen, M.J.W.,Bahnson, B.J.,Jain, M.K.; Kinetic and structural properties of disulfide engineered phospholipase a(2): insight into the role of disulfide bonding patterns.; Biochemistry, 44:3369-3379, 2005; PubMed: 15736947; DOI: 10.1021/bi0482147

Experimental method

X-RAY DIFFRACTION (2 Å)