1Y4I

Crystal structure of Citrobacter Freundii L-methionine-lyase

1Y4I の概要

• エントリーDOI: 10.2210/pdb1y4i/pdb
• 分子名称: methionine gamma-lyase, SULFATE ION (3 entities in total)
• 機能のキーワード: pyridoxal-5'-phosphate, plp-dependent enzyme, lyase
• 由来する生物種: Citrobacter freundii
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43317.07

構造登録者

Revtovich, S.V.,Mamaeva, D.V.,Morozova, E.A.,Nikulin, A.D.,Nikonov, S.V.,Garber, M.B.,Demidkina, T.V. (登録日: 2004-12-01, 公開日: 2005-06-14, 最終更新日: 2023-11-15)

主引用文献

Mamaeva, D.V.,Morozova, E.A.,Nikulin, A.D.,Revtovich, S.V.,Nikonov, S.V.,Garber, M.B.,Demidkina, T.V.
Structure of Citrobacter freundii L-methionine gamma-lyase.
Acta Crystallogr.,Sect.F, 61:546-549, 2005

PubMed Abstract: L-Methionine gamma-lyase (MGL) is a pyridoxal 5'-phosphate (PLP) dependent enzyme that catalyzes gamma-elimination of L-methionine. The crystal structure of MGL from Citrobacter freundii has been determined at 1.9 A resolution. The spatial fold of the protein is similar to those of MGLs from Pseudomonas putida and Trichomonas vaginalis. The comparison of these structures revealed that there are differences in PLP-binding residues and positioning of the surrounding flexible loops.

PubMed: 16511092
DOI: 10.1107/S1744309105015447

実験手法

X-RAY DIFFRACTION (1.9 Å)