1XY2

CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING

Summary for 1XY2

Entry DOI	10.2210/pdb1xy2/pdb
Descriptor	OXYTOCIN (2 entities in total)
Functional Keywords	hormone
Total number of polymer chains	1
Total formula weight	977.18
Authors	Cooper, S.,Blundell, T.L.,Pitts, J.E.,Wood, S.P.,Tickle, I.J. (deposition date: 1987-06-05, release date: 1988-04-16, Last modification date: 2017-11-29)
Primary citation	Wood, S.P.,Tickle, I.J.,Treharne, A.M.,Pitts, J.E.,Mascarenhas, Y.,Li, J.Y.,Husain, J.,Cooper, S.,Blundell, T.L.,Hruby, V.J.,Buku, A.,Fischman, A.J.,Wyssbrod, H.R. Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding. Science, 232:633-636, 1986 Cited by PubMed Abstract: Two crystal structures of deamino-oxytocin have been determined at better than 1.1A resolution from isomorphous replacement and anomalous scattering x-ray measurements. In each of two crystal forms there are two closely related conformers with disulfide bridges of different chirality, which may be important in receptor recognition and activation. PubMed: 3008332 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation