1XY1

CRYSTAL STRUCTURE ANALYSIS OF DEAMINO-OXYTOCIN. CONFORMATIONAL FLEXIBILITY AND RECEPTOR BINDING

1XY1 の概要

• エントリーDOI: 10.2210/pdb1xy1/pdb
• 分子名称: BETA-MERCAPTOPROPIONATE-OXYTOCIN (2 entities in total)
• 機能のキーワード: hormone
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 1986.36

構造登録者

Husain, J.,Blundell, T.L.,Wood, S.P.,Tickle, I.J.,Cooper, S.,Pitts, J.E. (登録日: 1987-06-05, 公開日: 1988-04-16, 最終更新日: 2024-11-20)

主引用文献

Wood, S.P.,Tickle, I.J.,Treharne, A.M.,Pitts, J.E.,Mascarenhas, Y.,Li, J.Y.,Husain, J.,Cooper, S.,Blundell, T.L.,Hruby, V.J.,Buku, A.,Fischman, A.J.,Wyssbrod, H.R.
Crystal structure analysis of deamino-oxytocin: conformational flexibility and receptor binding.
Science, 232:633-636, 1986

PubMed Abstract: Two crystal structures of deamino-oxytocin have been determined at better than 1.1A resolution from isomorphous replacement and anomalous scattering x-ray measurements. In each of two crystal forms there are two closely related conformers with disulfide bridges of different chirality, which may be important in receptor recognition and activation.

PubMed: 3008332

実験手法

X-RAY DIFFRACTION (1.04 Å)