1XXE

RDC refined solution structure of the AaLpxC/TU-514 complex

「1NZT」から置き換えられました

1XXE の概要

• エントリーDOI: 10.2210/pdb1xxe/pdb
• 分子名称: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION, 1,5-ANHYDRO-2-C-(CARBOXYMETHYL-N-HYDROXYAMIDE)-2-DEOXY-3-O-MYRISTOYL-D-GLUCITOL (3 entities in total)
• 機能のキーワード: lpxc; tu-514; lps; lipid a; lipopolysaccharide udp-3-o-acyl-n-acetylglucosamine deacetylase; metalloamidase; zinc metalloamidase, hydrolase
• 由来する生物種: Aquifex aeolicus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32690.89

構造登録者

Coggins, B.E.,McClerren, A.L.,Jiang, L.,Li, X.,Rudolph, J.,Hindsgaul, O.,Raetz, C.R.H.,Zhou, P. (登録日: 2004-11-04, 公開日: 2004-11-23, 最終更新日: 2022-03-02)

• 主引用文献: Coggins, B.E.,McClerren, A.L.,Jiang, L.,Li, X.,Rudolph, J.,Hindsgaul, O.,Raetz, C.R.H.,Zhou, P.; Refined Solution Structure of the LpxC-TU-514 Complex and pK(a) Analysis of an Active Site Histidine: Insights into the Mechanism and Inhibitor Design; Biochemistry, 44:1114-1126, 2005; PubMed: 15667205; DOI: 10.1021/bi047820z

実験手法

SOLUTION NMR