1XUX

Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogs

Summary for 1XUX

• Entry DOI: 10.2210/pdb1xux/pdb
• Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*(NMS)P*AP*CP*GP*C)-3') (2 entities in total)
• Functional Keywords: rna mimetic methylamino amide analog, dna
• Total number of polymer chains: 4
• Total formula weight: 12528.33

Authors

Pattanayek, R.,Sethaphong, L.,Pan, C.,Prhavc, M.,Prakash, T.P.,Manoharan, M.,Egli, M. (deposition date: 2004-10-26, release date: 2004-12-14, Last modification date: 2023-08-23)

• Primary citation: Pattanayek, R.,Sethaphong, L.,Pan, C.,Prhavc, M.,Prakash, T.P.,Manoharan, M.,Egli, M.; Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.; J.Am.Chem.Soc., 126:15006-15007, 2004; PubMed: 15547979; DOI: 10.1021/ja044637k

Experimental method

X-RAY DIFFRACTION (1.3 Å)