1XUW

Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogs

Summary for 1XUW

DescriptorDNA (5'-D(*GP*CP*GP*TP*AP*(NMT)P*AP*CP*GP*C)-3') (2 entities in total)
Functional Keywordsrna mimetic methylcarbamate amide analog, dna
Total number of polymer chains2
Total molecular weight6240.14
Authors
Pattanayek, R.,Sethaphong, L.,Pan, C.,Prhavc, M.,Prakash, T.P.,Manoharan, M.,Egli, M. (deposition date: 2004-10-26, release date: 2004-12-14, Last modification date: 2019-07-24)
Primary citation
Pattanayek, R.,Sethaphong, L.,Pan, C.,Prhavc, M.,Prakash, T.P.,Manoharan, M.,Egli, M.
Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.
J.Am.Chem.Soc., 126:15006-15007, 2004
PubMed: 15547979 (PDB entries with the same primary citation)
DOI: 10.1021/ja044637k
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.25 Å)
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Structure validation

ClashscoreRSRZ outliers00MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report