1XUW

Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogs

1XUW の概要

• エントリーDOI: 10.2210/pdb1xuw/pdb
• 分子名称: DNA (5'-D(*GP*CP*GP*TP*AP*(NMT)P*AP*CP*GP*C)-3') (2 entities in total)
• 機能のキーワード: rna mimetic methylcarbamate amide analog, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 6240.14

構造登録者

Pattanayek, R.,Sethaphong, L.,Pan, C.,Prhavc, M.,Prakash, T.P.,Manoharan, M.,Egli, M. (登録日: 2004-10-26, 公開日: 2004-12-14, 最終更新日: 2023-08-23)

• 主引用文献: Pattanayek, R.,Sethaphong, L.,Pan, C.,Prhavc, M.,Prakash, T.P.,Manoharan, M.,Egli, M.; Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues.; J.Am.Chem.Soc., 126:15006-15007, 2004; PubMed: 15547979; DOI: 10.1021/ja044637k

実験手法

X-RAY DIFFRACTION (1.25 Å)