1XS4

dCTP deaminase from Escherichia coli- E138A mutant enzyme in complex with dCTP

Summary for 1XS4

Entry DOI	10.2210/pdb1xs4/pdb
Related	1XS1 1XS6
Descriptor	Deoxycytidine triphosphate deaminase, MAGNESIUM ION, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	dctp deaminase, nucleotide metabolism, trimer, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	6
Total formula weight	131383.58
Authors	Johansson, E.,Fano, M.,Bynck, J.H.,Neuhard, J.,Larsen, S.,Sigurskjold, B.W.,Christensen, U.,Willemoes, M. (deposition date: 2004-10-18, release date: 2004-12-21, Last modification date: 2023-11-15)
Primary citation	Johansson, E.,Fano, M.,Bynck, J.H.,Neuhard, J.,Larsen, S.,Sigurskjold, B.W.,Christensen, U.,Willemoes, M. Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes J.Biol.Chem., 280:3051-3059, 2005 Cited by PubMed: 15539408 DOI: 10.1074/jbc.M409534200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.53 Å)

Structure validation