1XR3
Actinorhodin Polyketide Ketoreductase with NADP and the Inhibitor Isoniazid bound
Summary for 1XR3
Entry DOI | 10.2210/pdb1xr3/pdb |
Descriptor | ACTINORHODIN POLYKETIDE KETOREDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 4-(DIAZENYLCARBONYL)PYRIDINE (3 entities in total) |
Functional Keywords | protein-inhibitor complex, oxidoreductase |
Biological source | Streptomyces coelicolor |
Total number of polymer chains | 2 |
Total formula weight | 56343.08 |
Authors | Korman, T.P.,Hill, J.A.,Vu, T.N.,Tsai, S.C. (deposition date: 2004-10-13, release date: 2005-09-27, Last modification date: 2023-08-23) |
Primary citation | Korman, T.P.,Hill, J.A.,Vu, T.N.,Tsai, S.C. Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity. Biochemistry, 43:14529-14538, 2004 Cited by PubMed: 15544323DOI: 10.1021/bi048133a PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.71 Å) |
Structure validation
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