1XR3

Actinorhodin Polyketide Ketoreductase with NADP and the Inhibitor Isoniazid bound

1XR3 の概要

• エントリーDOI: 10.2210/pdb1xr3/pdb
• 分子名称: ACTINORHODIN POLYKETIDE KETOREDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 4-(DIAZENYLCARBONYL)PYRIDINE (3 entities in total)
• 機能のキーワード: protein-inhibitor complex, oxidoreductase
• 由来する生物種: Streptomyces coelicolor
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 56343.08

構造登録者

Korman, T.P.,Hill, J.A.,Vu, T.N.,Tsai, S.C. (登録日: 2004-10-13, 公開日: 2005-09-27, 最終更新日: 2023-08-23)

• 主引用文献: Korman, T.P.,Hill, J.A.,Vu, T.N.,Tsai, S.C.; Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity.; Biochemistry, 43:14529-14538, 2004; PubMed: 15544323; DOI: 10.1021/bi048133a

実験手法

X-RAY DIFFRACTION (2.71 Å)