1XOI

Human Liver Glycogen Phosphorylase A complexed with Chloroindoloyl glycine amide

Summary for 1XOI

Entry DOI	10.2210/pdb1xoi/pdb
Related	1EM6 1EXV
Descriptor	Glycogen phosphorylase, liver form, N-acetyl-beta-D-glucopyranosylamine, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
Functional Keywords	allosteric enzyme, glycogen storage disease, glycosyltransferase, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	195987.00
Authors	Wright, S.W.,Rath, V.L.,Gibbs, E.M.,Treadway, J.L. (deposition date: 2004-10-06, release date: 2005-04-12, Last modification date: 2024-02-14)
Primary citation	Wright, S.W.,Rath, V.L.,Genereux, P.E.,Hageman, D.L.,Levy, C.B.,McClure, L.D.,McCoid, S.C.,McPherson, R.K.,Schelhorn, T.M.,Wilder, D.E.,Zavadoski, W.J.,Gibbs, E.M.,Treadway, J.L. 5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization. Bioorg.Med.Chem.Lett., 15:459-465, 2005 Cited by PubMed: 15603973 DOI: 10.1016/j.bmcl.2004.10.048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation