1XOA

THIOREDOXIN (OXIDIZED DISULFIDE FORM), NMR, 20 STRUCTURES

1XOA の概要

• エントリーDOI: 10.2210/pdb1xoa/pdb
• 分子名称: THIOREDOXIN (1 entity in total)
• 機能のキーワード: electron transport, redox-active center
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11687.39

構造登録者

Jeng, M.-F.,Campbell, A.P.,Begley, T.,Holmgren, A.,Case, D.A.,Wright, P.E.,Dyson, H.J. (登録日: 1995-11-28, 公開日: 1996-06-10, 最終更新日: 2017-11-29)

主引用文献

Jeng, M.F.,Campbell, A.P.,Begley, T.,Holmgren, A.,Case, D.A.,Wright, P.E.,Dyson, H.J.
High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2:853-868, 1994

PubMed Abstract: Thioredoxin participates in thiol-disulfide exchange reactions and both oxidized thioredoxin (disulfide form) and reduced thioredoxin (dithiol form) are found under physiological conditions. Previous structural studies suggested that the two forms were extremely similar, although significant functional and spectroscopic differences exist. We therefore undertook high-resolution solution structural studies of the two forms of Escherichia coli thioredoxin in order to detect subtle conformational differences.

PubMed: 7812718
DOI: 10.1016/S0969-2126(94)00086-7

実験手法

SOLUTION NMR