1XO8

Solution structure of AT1g01470 from Arabidopsis Thaliana

1XO8 の概要

• エントリーDOI: 10.2210/pdb1xo8/pdb
• NMR情報: BMRB: 6339
• 分子名称: At1g01470 (1 entity in total)
• 機能のキーワード: structural genomics, protein structure initiative, center for eukaryotic structural genomics, psi, cesg, unknown function
• 由来する生物種: Arabidopsis thaliana (thale cress)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16560.99

構造登録者

Singh, S.,Cornilescu, C.C.,Tyler, R.C.,Cornilescu, G.,Tonelli, M.,Lee, M.S.,Markley, J.L.,Center for Eukaryotic Structural Genomics (CESG) (登録日: 2004-10-06, 公開日: 2004-10-19, 最終更新日: 2024-05-22)

主引用文献

Singh, S.,Cornilescu, C.C.,Tyler, R.C.,Cornilescu, G.,Tonelli, M.,Lee, M.S.,Markley, J.L.
Solution structure of a late embryogenesis abundant protein (LEA14) from Arabidopsis thaliana, a cellular stress-related protein
Protein Sci., 14:2601-2609, 2005

PubMed Abstract: We report the three-dimensional structure of a late embryogenesis abundant (LEA) protein from Arabidopsis thaliana gene At1g01470.1. This protein is a member of Pfam cluster PF03168, and has been classified as a LEA14 protein. LEA proteins are expressed under conditions of cellular stress, such as desiccation, cold, osmotic stress, and heat. The structure, which was determined by NMR spectroscopy, revealed that the At1g01470.1 protein has an alphabeta-fold consisting of one alpha-helix and seven beta-strands that form two antiparallel beta-sheets. The closest structural homologs were discovered to be fibronectin Type III domains, which have <7% sequence identity. Because fibronectins from animal cells have been shown to be involved in cell adhesion, cell motility, wound healing, and maintenance of cell shape, it is interesting to note that in plants wounding or stress results in the overexpression of a protein with fibronectin Type III structural features.

PubMed: 16155204
DOI: 10.1110/ps.051579205

実験手法

SOLUTION NMR