1XJV

Crystal structure of human POT1 bound to telomeric single-stranded DNA (TTAGGGTTAG)

Summary for 1XJV

• Entry DOI: 10.2210/pdb1xjv/pdb
• Descriptor: hT10 d(TTAGGGTTAG), Protection of telomeres 1 (3 entities in total)
• Functional Keywords: telomere; protein-dna complex; single-stranded dna, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9NUX5
• Total number of polymer chains: 2
• Total formula weight: 36312.12

Authors

Lei, M.,Podell, E.R.,Cech, T.R. (deposition date: 2004-09-25, release date: 2004-12-14, Last modification date: 2024-02-14)

• Primary citation: Lei, M.,Podell, E.R.,Cech, T.R.; Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection; Nat.Struct.Mol.Biol., 11:1223-1229, 2004; PubMed: 15558049; DOI: 10.1038/nsmb867

Experimental method

X-RAY DIFFRACTION (1.73 Å)