Crystal structure of human POT1 bound to telomeric single-stranded DNA (TTAGGGTTAG)

Summary for 1XJV

DescriptorhT10 d(TTAGGGTTAG), Protection of telomeres 1 (3 entities in total)
Functional Keywordstelomere; protein-dna complex; single-stranded dna, transcription-dna complex, transcription/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q9NUX5
Total number of polymer chains2
Total molecular weight36312.12
Lei, M.,Podell, E.R.,Cech, T.R. (deposition date: 2004-09-25, release date: 2004-12-14, Last modification date: 2011-07-13)
Primary citation
Lei, M.,Podell, E.R.,Cech, T.R.
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
Nat.Struct.Mol.Biol., 11:1223-1229, 2004
PubMed: 15558049 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb867
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.254220.3%2.7%11.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution