1XIA

COMPARISON OF BACKBONE STRUCTURES OF GLUCOSE ISOMERASE FROM STREPTOMYCES AND ARTHROBACTER

1XIA の概要

• エントリーDOI: 10.2210/pdb1xia/pdb
• 分子名称: D-XYLOSE ISOMERASE (1 entity in total)
• 機能のキーワード: isomerase(intramolecular oxidoreductase)
• 由来する生物種: Arthrobacter sp. NRRL
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 66928.33

構造登録者

Blow, D.M. (登録日: 1988-02-24, 公開日: 1988-04-16, 最終更新日: 2024-02-14)

主引用文献

Henrick, K.,Blow, D.M.,Carrell, H.L.,Glusker, J.P.
Comparison of backbone structures of glucose isomerase from Streptomyces and Arthrobacter.
Protein Eng., 1:467-469, 1987

PubMed Abstract: The C alpha backbones of the glucose isomerase molecules of Streptomyces rubiginosus and Arthrobacter have been determined by X-ray crystallography and compared. Each molecule is a tetramer of eight-stranded alpha/beta barrels, and the mode of association of the tetramers is identical in each case. The Arthrobacter electron density shows four additional amino acids at the carboxyl terminus. There is also an insertion of six amino acids at position 277, and two individual insertions at about positions 348 and 357 (numbering according to the Streptomyces structure). There is a close structural homology throughout the whole molecule, which is most accurate up to position 325. The r.m.s. displacement for 315 homologous C alpha positions up to this position is 0.92 A.

PubMed: 3508294
DOI: 10.1093/protein/1.6.467

実験手法

X-RAY DIFFRACTION (2.3 Å)