1XC9

Structure of a high-fidelity polymerase bound to a benzo[a]pyrene adduct that blocks replication

1XC9 の概要

• エントリーDOI: 10.2210/pdb1xc9/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900003
• 分子名称: DNA primer strand, DNA template strand with benzo[a]pyrene adduct, DNA polymerase I, ... (8 entities in total)
• 機能のキーワード: dna polymerase i; dna replication; klenow fragment; benzo[a]pyrene; benzopyrene; dna lesion; translation replication, transferase-dna complex, transferase/dna
• 由来する生物種: Geobacillus stearothermophilus
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 74818.99

構造登録者

Hsu, G.W.,Huang, X.,Luneva, N.P.,Geacintov, N.E.,Beese, L.S. (登録日: 2004-09-01, 公開日: 2004-12-14, 最終更新日: 2023-08-23)

• 主引用文献: Hsu, G.W.,Huang, X.,Luneva, N.P.,Geacintov, N.E.,Beese, L.S.; Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication; J.Biol.Chem., 280:3764-3770, 2005; PubMed: 15548515; DOI: 10.1074/jbc.M411276200

実験手法

X-RAY DIFFRACTION (1.9 Å)