1XC5

Solution Structure of the SMRT Deacetylase Activation Domain

Summary for 1XC5

DescriptorNuclear receptor corepressor 2 (1 entity in total)
Functional Keywordsfour-helix structure, three-helix triangle, transcription corepressor
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q9Y618
Total number of polymer chains1
Total molecular weight8578.96
Authors
Codina, A.,Love, J.D.,Li, Y.,Lazar, M.A.,Neuhaus, D.,Schwabe, J.W.R. (deposition date: 2004-09-01, release date: 2005-05-03, Last modification date: 2011-07-13)
Primary citation
Codina, A.,Love, J.D.,Li, Y.,Lazar, M.A.,Neuhaus, D.,Schwabe, J.W.R.
Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors
Proc.Natl.Acad.Sci.Usa, 102:6009-6014, 2005
PubMed: 15837933 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0500299102
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers6711.4%37.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 1xc5
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Molmil generated image of 1xc5
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Molmil generated image of 1xc5
rotated about y axis by 90°