1XBZ

Crystal structure of 3-keto-L-gulonate 6-phosphate decarboxylase E112D/R139V/T169A mutant with bound L-xylulose 5-phosphate

1XBZ の概要

• エントリーDOI: 10.2210/pdb1xbz/pdb
• 関連するPDBエントリー: 1XBV 1XBX 1XBY
• 分子名称: 3-Keto-L-Gulonate 6-Phosphate Decarboxylase, MAGNESIUM ION, L-XYLULOSE 5-PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: tim barrel, unknown function
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47482.71

構造登録者

Wise, E.L.,Yew, W.S.,Akana, J.,Gerlt, J.A.,Rayment, I. (登録日: 2004-08-31, 公開日: 2005-04-26, 最終更新日: 2024-02-14)

• 主引用文献: Wise, E.L.,Yew, W.S.,Akana, J.,Gerlt, J.A.,Rayment, I.; Evolution of enzymatic activities in the orotidine 5'-monophosphate decarboxylase suprafamily: structural basis for catalytic promiscuity in wild-type and designed mutants of 3-keto-L-gulonate 6-phosphate decarboxylase; Biochemistry, 44:1816-1823, 2005; PubMed: 15697207; DOI: 10.1021/bi0478143

実験手法

X-RAY DIFFRACTION (1.8 Å)