1WT5
The Crystal Structure Of A Humanized Antibody Fv 528
Summary for 1WT5
Entry DOI | 10.2210/pdb1wt5/pdb |
Descriptor | ANTI EGFR ANTIBODY FV REGION (3 entities in total) |
Functional Keywords | humanized antibody, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 55253.70 |
Authors | Makabe, K.,Tsumoto, K.,Asano, R.,Kondo, H.,Kumagai, I. (deposition date: 2004-11-16, release date: 2005-05-16, Last modification date: 2011-07-13) |
Primary citation | Makabe, K.,Nakanishi, T.,Tsumoto, K.,Tanaka, Y.,Kondo, H.,Umetsu, M.,Sone, Y.,Asano, R.,Kumagai, I. Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528 J.Biol.Chem., 283:1156-1166, 2008 Cited by PubMed: 17947238DOI: 10.1074/jbc.M706190200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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