1WT5

The Crystal Structure Of A Humanized Antibody Fv 528

Summary for 1WT5

• Entry DOI: 10.2210/pdb1wt5/pdb
• Descriptor: ANTI EGFR ANTIBODY FV REGION (3 entities in total)
• Functional Keywords: humanized antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 55253.70

Authors

Makabe, K.,Tsumoto, K.,Asano, R.,Kondo, H.,Kumagai, I. (deposition date: 2004-11-16, release date: 2005-05-16, Last modification date: 2011-07-13)

• Primary citation: Makabe, K.,Nakanishi, T.,Tsumoto, K.,Tanaka, Y.,Kondo, H.,Umetsu, M.,Sone, Y.,Asano, R.,Kumagai, I.; Thermodynamic consequences of mutations in vernier zone residues of a humanized anti-human epidermal growth factor receptor murine antibody, 528; J.Biol.Chem., 283:1156-1166, 2008; PubMed: 17947238; DOI: 10.1074/jbc.M706190200

Experimental method

X-RAY DIFFRACTION (2.1 Å)