1WQ1
RAS-RASGAP COMPLEX
Summary for 1WQ1
Entry DOI | 10.2210/pdb1wq1/pdb |
Descriptor | H-RAS, P120GAP, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | ras, gap, signal transduction, growth regulation, gtp hydrolysis, transition state, complex (gtp-binding-gtpase activation), complex (gtp-binding-gtpase activation) complex, complex (gtp-binding/gtpase activation) |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side: P01112 Cytoplasm: P20936 |
Total number of polymer chains | 2 |
Total formula weight | 57649.95 |
Authors | Scheffzek, K.,Ahmadian, M.R.,Kabsch, W.,Wiesmueller, L.,Lautwein, A.,Schmitz, F.,Wittinghofer, A. (deposition date: 1997-07-03, release date: 1998-07-15, Last modification date: 2023-08-09) |
Primary citation | Scheffzek, K.,Ahmadian, M.R.,Kabsch, W.,Wiesmuller, L.,Lautwein, A.,Schmitz, F.,Wittinghofer, A. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants. Science, 277:333-338, 1997 Cited by PubMed: 9219684DOI: 10.1126/science.277.5324.333 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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