1WER

RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP

Summary for 1WER

Entry DOI	10.2210/pdb1wer/pdb
Descriptor	P120GAP (2 entities in total)
Functional Keywords	gtpase activation, ras, gap, signal transduction, growth regulation, cancer
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P20936
Total number of polymer chains	1
Total formula weight	38223.28
Authors	Scheffzek, K.,Lautwein, A.,Kabsch, W.,Ahmadian, M.R.,Wittinghofer, A. (deposition date: 1996-11-20, release date: 1997-12-31, Last modification date: 2024-02-14)
Primary citation	Scheffzek, K.,Lautwein, A.,Kabsch, W.,Ahmadian, M.R.,Wittinghofer, A. Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras. Nature, 384:591-596, 1996 Cited by PubMed: 8955277 DOI: 10.1038/384591a0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation