1WBU
Fragment based lead discovery using crystallography
Summary for 1WBU
Entry DOI | 10.2210/pdb1wbu/pdb |
Descriptor | RIBONUCLEASE, 5-AMINO-1H-PYRIMIDINE-2,4-DIONE (3 entities in total) |
Functional Keywords | ribonuclease, inhibitor, endonuclease, glycoprotein, hydrolase |
Biological source | BOS TAURUS (BOVINE) |
Cellular location | Secreted: P61824 |
Total number of polymer chains | 2 |
Total formula weight | 27670.85 |
Authors | Cleasby, A.,Hartshorn, M.J.,Murray, C.W.,Jhoti, H.,Tickle, I.J. (deposition date: 2004-11-05, release date: 2005-01-27, Last modification date: 2011-07-13) |
Primary citation | Hartshorn, M.J.,Murray, C.W.,Cleasby, A.,Frederickson, M.,Tickle, I.J.,Jhoti, H. Fragment-Based Lead Discovery Using X-Ray Crystallography J.Med.Chem., 48:403-, 2005 Cited by PubMed: 15658854DOI: 10.1021/JM0495778 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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